2024
Effect of peanut stilbenoids, arachidin-1 and arachidin-3, on Streptococcus mutans growth and acid production
Reed KB, Pruitt E, KC HR, Sharma AR, Medina-Bolivar F, & Shields RC
Natural Product Research
Construction of an arrayed CRISPRi library as a resource for essential gene function studies in Streptococcus mutans
St. Pierre J, Roberts J, Alam MA, & Shields RC
Microbiology Spectrum
2023
Development and antibacterial properties of 4-[4-(anilinomethyl)-3-phenylpyrazol-1-yl] benzoic acid derivatives as fatty acid biosynthesis inhibitors
Roy S, KC HR, Roberts J, Hastings J, Gilmore DF, Shields RC, & Alam MA
Journal of Medicinal Chemistry
2022
Interspecies competition in oral biofilms mediated by Streptococcus gordonii extracellular deoxyribonuclease SsnA
Rostami N, Shields RC, Serrage HJ, Lawler C, Brittan JL, Yassin S, Ahmed H, Truemann A, Thompson P, Waldron KJ, Nobbs AH, & Jakubovics NS
npj Biofilms and Microbiomes
Investigating CRISPR spacer targets and their impact on genomic diversification of Streptococcus mutans
Walker AR & Shields RC
Frontiers in Genetics
Activation of TnSmu1, an integrative and conjugative element, by an ImmR-like transcriptional regulator in Streptococcus mutans
King S, Quick A, King K, Walker AR, & Shields RC
Microbiology
Identification and Analysis of Essential Genes in Streptococcus mutans with Transposon Sequencing
Walker AR & Shields RC
Essential Genes and Genomes
2020
Repurposing the Streptococcus mutans CRISPR-Cas9 system to understand essential gene function
Shields RC, Walker AR, Maricic N, Chakraborty B, Underhill SAM, & Burne RA
PLOS Pathogens
Peptides encoded in the Streptococcus mutans RcrRPQ operon are essential for thermotolerance
Shields RC, Kim JN, Ahn SJ, & Burne RA
Microbiology
2019
Carbohydrate and PepO control bimodality in competence development by Streptococcus mutans
Underhill SAM, Shields RC, Burne RA, & Hagen SJ
Molecular Microbiology
Fluorescence tools adapted for monitoring the behaviors of Streptococcus species
Shields RC, Kaspar JR, Underhill SAM, Lee K, & Burne RA
Applied and Environmental Microbiology
The bare necessities: uncovering essential and condition-critical genes with transposon sequencing
Shields RC & Jensen PA
Molecular Oral Microbiology
2018
Intracellular signaling by the comRS system in Streptococcus mutans genetic competence
Underhill SAM, Shields RC, Kaspar JR, Haider M, Burne RA, & Hagen SJ
mSphere
Competence inhibition by the XrpA peptide encoded within the comX gene of Streptococcus mutans
Kaspar JR, Shields RC, & Burne RA
Molecular Microbiology
Genomewide identification of essential genes and fitness determinants of Streptococcus mutans UA159
Shields RC, Zeng L, Culp DJ, & Burne RA
mSphere
Genome-wide screens reveal new gene products that influence genetic competence in Streptococcus mutans
Shields RC, O’Brien G, Maricic N, Kesterson AE, Grace M, Hagen SJ, & Burne RA
Journal of Bacteriology
2017
Intercellular communication via the comX-inducing peptide (XIP) of Streptococcus mutans
Kaspar JR, Underhill SAM, Shields RC, Reyes A, Rosenzweig S, Hagen SJ, & Burne RA
Journal of Bacteriology
A new arginine-based dental adhesive system: formulation, mechanical and anti-caries properties
Geraldeli S, Soares EF, Alvarez AJ, Tanaz F, Shields RC, Sinhoreti, MAC, & Nascimento MM
Journal of Dentistry
A critical role for extracellular DNA in dental plaque formation
Rostami N, Shields RC, Yassin SA, Hawkins AR, Bowen L, Luo TL, Rickard AH, Holliday R, Preshaw PM, & Jakubovics NS
Journal of Dental Research
2016
Growth of Streptococcus mutans in biofilms alters peptide signalling at the sub-population level
Shields RC, & Burne RA
Frontiers in Microbiology
2015
Bidirectional signalling in the competence regulatory pathway of Streptococcus mutans
Son M, Shields, RC, Ahn, SJ, Burne, RA, & Hagen, SJ
FEMS Microbiology Letters
Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and Streptococcus mutans
Shields RC, & Burne RA
FEMS Microbiology Letters
Biofilms in chronic rhinosinusitis: what is new and where next?
Ramakrishnan Y, Shields RC, Elbadawey MR, & Wilson JR
The Journal of Laryngology and Otology
2013
Life after death: the critical role of extracellular DNA in microbial biofilms
Jakubovics NS, Shields RC, Rajarajan N, & Burgess JG
Letters in Applied Microbiology
Efficacy of a marine bacterial nuclease against biofilm forming microorganisms isolated from chronic rhinosinusitis
Shields RC, Mokhtar N, Ford M, Hall MJ, Burgess JG, ElBadawey MR, & Jakubovics NS
PLOS ONE
2012
Removal of biofilms from tracheoesophageal speech valves using a novel marine microbial deoxyribonuclease
Shakir A, Elbadawey MR, Shields RC, Jakubovics NS, & Burgess JG
Otolaryngology and Head and Neck Surgery